Utilizing Nanoparticle Catalyzed TMB/H2O2 System for Determination of Aspirin in Exhaled Breath Condensate

Background: According to the poison center data for most countries, more than thousands of people’s exposure aspirin or salicylate-containing products. So, this work aimed was offer a rapid colorimetric method monitoring concentration in exhaled breath condensate (EBC). Methods: A based on redox reaction catalyzed by nanoparticles validated analysis aspirin. 3,3 ,5,5 –Tetramethyl benzidine /H2 O2 and sodium dodecyl sulfate modified silver were used as reagents catalyst, respectively. Results: Detection mechanism using system is inhibitory effect signal intensity systems. Since decrement proportional level, proposed its quantification EBC samples. This shows linear relationship with range 10‒250 mg.L−1 relative standard deviation < 3.5%. Conclusion: has great potential determination due some features such high reliability, fast response time.